Oct 14, 2020
Dr. Giselle Petzinger on Exercise for Parkinson's Disease
Play • 1 hr 19 min

Giselle Petzinger, MD, an associate professor of Neurology at the University of Southern California and today’s guest, studies the extensive effects of how different types of exercise, in particular skill-based exercise, can affect the clinical outcome for people with Parkinson’s disease.

Dr. Petzinger's work focuses on understanding how to promote brain repair after injury, particularly in the context of Parkinson's disease. She is currently investigating ways to enhance neuroplasticity in a preclinical model of the disease. She has examined the role of exercise in Parkinson's disease, with emphasis on how different types of exercise affect distinct regions of the brain. Her work has implications for improving the quality of life of patients diagnosed with the neurological disorder — a condition for which there is no cure.

In this episode, we discuss...

  • 00:06:57 - What is Parkinson’s disease?
  • 00:11:57 - How symptoms of Parkinson’s disease generally only appear when ~50% of dopamine-secreting neurons in substantia nigra are lost. 1
  • 00:14:57 - How other circuits in the brain can compensate for the loss of function of the substantia nigra.
  • 00:18:37 - Prevalence and hereditary risk factors of Parkinson’s disease.
  • 00:21:25 - How epidemiological studies have linked increased Parkinson’s disease risk with exposure to pesticides, herbicides, solvents, and certain heavy metals such as manganese. 1
  • 00:26:57 - How exercise can lower the risk of developing Parkinson’s disease. 1 2 3
  • 00:35:38 - How skill-based exercise, such as yoga, Tai chi, boxing, tango or skateboarding may play a special role in ameliorating some of the effects of the disease by driving circuit-specific effects, by creating top-down cognitive challenge for skills involved in a patient's movement through space.
  • 00:47:49 - How serum BDNF significantly increases in Parkinson’s patients after 1 month of treadmill exercise and why this might mean better cognitive function. 1 2
  • 00:58:33 - How treadmill exercise with heart rate 80-85% maximum for at least 3x per week slowed the progression of Parkinson’s disease symptoms. 1
  • 01:01:31 - Why exercise may not fully replace the use of medications.
  • 01:09:58 - How the omega-3 fatty acid DHA has some preclinical evidence suggesting it may reduce motor-symptoms and dyskinesia in Parkinson’s disease. 1 2 3 4
  • 01:12:12 - How patients with Parkinson’s disease have higher levels of inflammatory biomarkers and how this might contribute to the disease. 1

Click here to get this episode's show notes and transcript

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Dawn Kernagis and Ken Ford
Episode 117: Julie Anderson talks about her research into aging and neurodegenerative diseases
Our guest today is Dr. Julie Andersen, who is best known for her research into aging and age-related diseases. A professor at the Buck Institute Buck Institute for Research on Aging, an independent biomedical research institute that researches ways to extend the healthy years of life, Julie and her colleagues at Buck have focused on understanding the underlying age-related processes driving neurodegenerative diseases in order to identify novel therapeutics. Because our conversation with Julie was so fascinating and long, we have divided it into two parts. In today’s part one of her interview, we talk to Julie about her youth and early career. We also talk to her about the potential of of rapamycin to protect brain cells and mitochondria in a mouse model of Parkinson’s disease as well as her thoughts about the Amyloid Cascade Hypothesis. In part two, which will go live in a few weeks, we have an in-depth conversation with Julie about her research into the neuroprotective properties of urolithin A. In terms of Julie’s background, she received her Ph.D. from UCLA and did her post-doc in the department of neurology at Harvard. In 2000 Julie joined the Buck Institute. Show notes: [00:03:33] Dawn opens the interview asking if it is true that Julie was a quiet kid who normally sat in the back of the classroom. [00:03:52] Dawn mentions that Julie was born in Montana but that she grew up in northern Idaho. Dawn asks what it was that brought Julie’s family to Idaho. [00:04:29] Dawn asks Julie what interests she had growing up. [00:05:05] Ken remarks on the fact that one of Julie’s favorite books is a biography of Clementine, Winston Churchill’s wife, and asks where Julie’s interest in Clementine came from. [00:05:46] Dawn mentions that for Julie’s undergraduate degree, she went to Washington State University, where her father was a professor. Dawn asks if Julie knew from the start that she was going to focus her undergraduate studies on plant physiology. [00:07:03] Ken asks Julie took her to UCLA for her Ph.D. [00:08:16] Dawn asks Julie what led to travel across the country to Boston for her post-doc. [00:09:26] Julie explains why she eventually returned to California after her Ph.D. [00:11:32] Dawn asks Julie to tell the story of how meeting someone she described as “a fellow nerd” at an aging conference eventually led her to taking a position at the Buck Institute. [00:14:34] Ken remarks that Julie must like working at the Buck, given she has remained there for the last 20 years. Julie describes what is it about the Buck Institute that makes it such a special place. [00:17:51] Dawn mentions that for the past 20 years, Julie and her lab at Buck have looked at a lot of different aspects of neurodegeneration, with a heavier concentration on autophagy in the past five years. Dawn goes on to mention that Julie has especially been investigating a natural bioactive known as urolithin A. Before diving into all of this work specifically, Dawn asks Julie, what drew her to the study of neurodegeneration to begin with. [00:19:55] Ken asks what prompted Julie’s current focus on autophagy. [00:24:11] Dawn explains that degradation of damaged mitochondria via lysosomal autophagy is a key cellular pathway in the maintenance of mitochondrial homeostasis.  Disruption of this pathway contributes to the progressive cell loss that is associated with Parkinson’s disease. She goes on to mention that Julie published the results of a study in 2015that found rapamycin can protect brain cells and mitochondria in a mouse model of Parkinson’s disease. Julie explains the significance of this study and talks about the importance of rapamycin in the research of therapies for Parkinson’s disease. [00:30:44] Dawn asks Julie to explain the concept, and the significance of, transcription factor EB (TFEB), which is a protein that is encoded in humans by the TFEB gene, and is a master regulator of autophagy and lysosom...
50 min
Bulletproof Radio
Bulletproof Radio
Dave Asprey
Finding Pleasure in Fasting, Sex and Spirituality – Nadia Bolz-Weber with Dave Asprey : 785
In this episode of Bulletproof Radio, Lutheran Pastor Nadia Bolz-Weber shares her relationship with religion that’s refreshingly frank. Nadia, a former addict and stand-up comedian, founded the House for All Sinners & Saints church in Denver, Colorado, in 2008. She led the congregation for a decade, then retired from church leadership to continue her work as a public theologian. She’s also the author of three New York Times bestselling books in which she considers the nature of sex, pleasure, spirituality–and even shame. She explores and embraces a pretty expansive worldview. I find her fascinating–from her “Sarcastic Lutheran” social handles to "The Confessional" podcast she hosts–and wanted to get her unique perspective on fasting, lack and going without. On Fasting: “My own profound experience of fasting actually isn’t part of the Christian tradition,” Nadia explains. “It's just 48 hours of prayer and fasting, and I'm outside on the ridge of this mountain, not a mountain, but the hills. With just a bedroll. For two days. I stay in one spot. Being a New York Times bestselling author does jack shit for you.” On the Body: “It's baffling to me that Christianity became such a body hating, pleasure-hating religion, when the whole story behind Christianity is, God decided to have a human body,” she says. “And then we say they're evil if we actually believe God decided out of all things to slip into skin and walk among us. It's just crazy to me.” On Sex: “I was walking down the street in London, all this stuff is swirling in my head, and I was just like so amazed by how good it was for me to be having sex again,” she says. “And then I thought, “Why did the church make me sign a paper saying I wouldn't do this. How is it better for my church if I'm not getting laid?” That makes no sense whatsoever.”  In her most recent book, “Shameless: A Sexual Reformation: A Case for Not Feeling Bad About Feeling Good (About Sex)“ she writes about the complicated relationship people have with sex and pleasure, and Christianity’s often distorted reality of that. Listen on to our conversation and to learn how to sift through life’s mixed messages about faith and pleasure to find what brings you personal meaning. Enjoy! And get more resources at WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Fast Fitness:, use code DAVE to get an extra $100 off any existing promotions Great Skin:, use code DAVE20 for 20% off storewide Functional Soda:, get 20% off PLUS free shipping on the best-selling Variety Pack DAVE ASPREY’S NEW BOOK! Order “Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be” and enroll in Dave Asprey’s first ever Fasting Challenge:
45 min
Live Long and Master Aging
Live Long and Master Aging
HealthSpan Media
Leslie Kenny: Biohacking and spermidine for life-enhancement
After a diagnosis of lupus, in her 30s, Leslie Kenny was told she had a life expectancy of five years. The prognosis focussed the Berkeley and Harvard grad's mind like never before. Long before biohacking was a thing, Leslie set about changing her lifestyle, embracing safe, natural solutions, in a fight for her life. Now 56, she is aging well, healthy and a fully signed up biohacker. She is the founder of Oxford Healthspan, a UK-based company, working with leading scientists to identify safe compounds as nutritional supplements. In this LLAMA podcast conversation with Peter Bowes, Leslie discusses her own unique journey, as well as the science and life-enhancing potential of spermidine, a compound that has been shown to be vital to myriad bodily functions.  Recorded: January 19, 2021 | Read a transcript* *and show notes at the LLAMA podcast website. This episode is brought to you by AgeUp, a new financial product that provides guaranteed supplemental income for people who worry about the financial impact of longevity. To find out more, visit Topics covered in this interview include: * Leslie's journey from Swiss banking to biohacking  * Facing up to Lupus and a five-year life expectancy  * One's own mortality and the limits of longevity * Pillars of preventative healthcare: sleep, movement , diet, friendship, family * Why your health is your wealth * Discovering the polyamine compound spermidine and establishing Oxford Healthspan  * Where does the name spermidine come from and what is it?  * The evidence for the benefits of spermidine - epidemiological  studies and clinical trials  * Is spermidine supplementation safe?  * How do consumers make decisions about which supplements to take?   * Living life with the promise of healthspan rather than lifespan  * Disease prevention versus disease care  * The lifestyle of a biohacker - sleep hygiene, good food, lowered stress The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
41 min
Gut Health Gurus Podcast
Gut Health Gurus Podcast
Kriben Govender
Morley Robbins on Copper Deficiency and Mineral Balance
A fascinating discussion with Morley Robbin on Copper, Iron and Mineral Balance and how they impact our health.     Bio:    Morley Robbins is the creator of The Root Cause Protocol.   Morley (aka. “Magnesium Man”) is one of the foremost experts on Magnesium’s role in the body, and the delicate dance Magnesium plays with Iron, Copper, and Calcium.   In 2012, Morley founded the Magnesium Advocacy Group (   And he remains the de facto leader of the Magnesium Advocacy Group on Facebook, with over 175,000+ members (and growing daily).   As a certified health coach with an expertise in Hair Tissue Mineral Analysis (HTMA), Morley has performed over 4,500 one-on-one consultations with clients from around the world.   Topics discussed:   * Who is Morley Robbins? * The Importance of Minerals * Magnesium * Health Freedom - Medical Independence * Copper- Ceruloplasmin * Iron * Oxygen - Metals * Mitochondria * Iron Toxicity * Copper - Iron Interaction * How to Measure Iron Status in the body? * Copper - Iron and Oxygen * Anti oxidant Enzymes * Oxidative Stress , Inflammation and Cell Death * Metabolic Dysfunction * Why does the body consume magnesium when stressed? * Sympathetic and Parasympathetic Nervous system * Mineral Activation of Nervous System * The oldest hormone in the body * Calcium and Magnesium status * The Definition of Stress * Iron and Stress * The addition of iron to food * pH and energy * Healing is Voltage * Energy Vibration * pH and Energy * What is too much Iron in the diet doing? * Macrophages * Response to Infection * Mitochondrial water production * Inflammation and Hydrogen Peroxide * Hydrogen and the Microbiome * The Great Oxygen Event * Multi- Copper- Oxidases * Cholesterol * Gut Bacteria and Multi Copper Oxidases * Enzymes and Quantum Biology * Mineral and Enzyme Connection * Physics and Biology * Hydrogen Peroxide and Iron Reaction * The Copper Story * Stephanie Seneff * Glyphosate and Copper Connection * Ceruloplasmin * Ascorbic Acid and Copper * Factors disrupting Ceruloplasmin * The Root Cause Protocol * High Fructose Corn Syrup and Gut Health * How much copper do we need? * Ascorbic Acid vs Vitamin C * Source of Real Vitamin C * Kakadu Plum * Camu Camu * Tyrosinase Enzyme * Ancestral Eating and Dealing with Emotional issues * Gut Dysbiosis and Iron   Brought to you by:   Nourishme Organics your online shop for Gut Health Products   Shop online today and use code rootcause for 10% off   Connect with Morley Robbins   Website-   Connect with Kriben Govender:    Facebook- Instagram- Youtube- Gut Health Gurus Facebook Group: Deuterium Depletion Support Group :     Download links               If you enjoyed this episode and would like to show your support:   1) Please subscribe on Apple Podcasts, give us 5 stars and leave a positive review     Instructions:   - Click this link   - Click "View in Itunes" button on the left-hand side - This will open the Itunes app - Click the "Subscribe" button - Click on "Ratings and Reviews" tab - Click on "Write a Review" button   Non-Itunes users can leave a Google Review here:     2) Subscribe, like and leave a positive comment on Youtube   3) Share your favourite episode on Facebook, Instagram, and Stories 4) Let your friends and family know about this Podcast by email, text, messenger etc   Thank you so much for your support. It means the world to us.
1 hr 5 min
The Rich Roll Podcast
The Rich Roll Podcast
Rich Roll
Feels Good Man! Arthur Jones & Giorgio Angelini On The Controversial Meme That Changed The World
In a spark of creativity, cartoonist Matt Furie created an innocent, loving frog he named Pepe. What came next is so insane, it literally bent reality. Filmmakers Arthur Jones & Giorgio Angelini wanted to understand how this sweet and relatively obscure indie comic book character morphed into an infamous symbol of hate—and a meme that changed the world. The result is Feels Good Man—a filmmaking triumph and one of the best documentaries I’ve seen in years. Premiering at last year’s Sundance, where it picked up the U.S. Documentary Special Jury Award for Emerging Filmmaker, it’s the surreal story of Pepe The Frog. How it migrated across the internet, evolving into an unwitting avatar of chaos and a lever for radicalization. It’s about its creator Matt Furie’s efforts to reclaim his creation. And Pepe’s slow transmogrification back into a hieroglyph of positivity. But beneath the surface, Feels Good Man is about artistic agency. It’s about the journey from passivity to participation. A sociological excavation of how culture spreads from mind to mind, it’s also an archeological dig into the indelible power of an idea. How a meme adopted by a regressive internet subculture spilled into the real world, shifted the political landscape, and ultimately tipped a presidential election. The film is an absolute must-see. I wanted to know more. So today Arthur and Giorgio take us behind the looking glass on Pepe’s Frankenstein-meets-Alice-In-Wonderland journey. This is a conversation about the complicated relationship between internet culture and the real world. It’s about the strange relationship between comic book artists, arch druids, data scientists, intellectual property lawyers, and alt-right mouthpieces. It’s about memetics—how memes drive cultural evolution in parallel with how genes influence human evolution. And, in this case, how one meme was perniciously coopted to democratize electoral engagement, enervating passive supporters into active participants. But more than anything, this is about the war between cynicism and hope. And why, to coin Matt Furie, you gotta go hardcore happy. The visually inclined can watch our exchange on YouTube. And as always, the podcast streams wild and free on Apple Podcasts and Spotify. I don’t understand why everyone isn’t talking about this movie and the ideas it presents. This conversation is my attempt to change that. Peace + Plants, Listen, Watch & Subscribe Apple Podcasts | YouTube | Spotify | Stitcher | Google Podcasts Thanks to this week’s sponsors: Daily Harvest: Daily Harvest makes it easy to eat more fruits and vegetables with thoughtfully sourced, chef-crafted foods that are ready in five minutes or less. Go to and enter promo code richroll to get $25 off your first box. ROKA: Cutting edge eyewear & apparel built for top performance. Ultralight construction. Arms-Up Design. Official USAT Partner. If you’re active like me and wear prescription eyeglasses and sunglasses, ROKA combines the no-slip performance you’ve been waiting for with fashionable design. Visit and enter code RichRoll for 20% off. Theragun: With an OLED screen, personalized Theragun app, and the quiet and power you need, there is no substitute for the Theragun Gen 4, starting at only $199. Experience the percussive therapy device that’s unlike anything you’ve ever felt at joovv: Enhance your health, recovery, and sleep with Joovv light therapy. Discover the science of light therapy and how it can help you reach your health & fitness goals. For a limited time, Joovv wants to hook you up with an exclusive discount on your first order: just go and apply my code RICHROLL to your qualifying order. Exclusions apply, limited time only. SHOW NOTES: * Feels Good Man: Website * Feels Good Man Trailer * New York Times: ‘Feels Good Man’ Review: The Evolution of a Poisonous Frog * AV Club: The internet’s most infamous frog gets a documentary redemption in Feels Good Man * Variety: ‘Feels Good Man’: Film Review * Filmmaker Magazine: “You Can’t DM People on 4chan”: Arthur Jones and Giorgio Angelini on Pepe the Frog Documentary Feels Good Man * Sundance Film Festival: Meet the Artist: Arthur Jones * HN: A Conversation With Arthur Jones & Giorgio Angelini (FEELS GOOD MAN) * The Moveable Feast: Interview: Arthur Jones & Giorgio Angelini on Putting a Human Face on Pepe the Frog in “Feels Good Man” * The Guardian: Feels Good Man: The disturbing story behind the rise of Pepe the Frog * Collider: ‘Feels Good Man’ Review: We Should Probably Burn the Internet to the Ground I'm proud to announce my new book 'Voicing Change'. To learn more & pre-order now, visit, There are a few simple ways you can support the show and the content we strive to craft and share every single week Subscribe & Review: Please make sure to review, share comments and subscribe to the show on the various platforms (Apple Podcasts, YouTube & Spotify). This helps tremendously! Patronize Our Sponsors: Supporting the companies that support the show! For a complete list of all RRP sponsors and their respective vanity URLs and discount codes, click the ‘Sponsors’ tab in the ‘Shop’ menu. Spread The Word: Help grow our reach by sharing your enthusiasm for the podcast and/or your favorite episodes by posting about it on social media. Thank The Team: I do not do this alone. Send your love to Jason Camiolo for production, audio engineering and show notes; Margo Lubin and Blake Curtis for video, editing and graphics; portraits by Ali Rogers & Davy Greenberg; and theme music by Tyler Piatt. Trapper Piatt & Hari Mathis. 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1 hr 59 min
Siim Land Podcast
Siim Land Podcast
Siim Land
#225 Why Does Cholesterol Rise While Fasting, Sleep Problems on Carnivore, Best Time to Start Eating - Live Q&A
This episode is a recording of my YouTube live stream on the 25th of January, 2021. Timestamps: * 00:17 Updates to Metabolic Autophagy * 02:25 Benefits of Boron Foods * 04:37 Benefits of Lion's Mane * 08:50 Sleep Problems on Carnivore * 15:45 Fasting Against Radiation * 17:43 Best Fasting for Intelligence * 22:50 Thoughts on the Pandemic * 27:13 Best Time to Start Eating When Fasting * 30:14 How to Lower Triglycerides * 36:00 Autophagy 16/8 vs 24 Hours * 43:00 Best Proteins for Vegetarians * 46:00 Why Cholesterol Rises During Fasting * 50:00 Liver VS Oysters Nutrients * 52:55 How to Increase Your Intelligence * 55:50 Too Much Cold Exposure And much more Here are the links to the podcast on all platforms * Link to the Audio Podcast on iTunes and Stitcher * Link to the podcast on Spotify * Link to the podcast on CastBox * Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body. With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That’s an AMAZING value. And I promise that deal is ONLY available on this specific website, Click Here to Support the Show on Patreon! Show Notes * Stronger by Stress on Amazon * Stronger by Stress Audiobook * The Immunity Fix on Amazon * Get Magnesium Breakthrough for a 10% Discount! * Use Code SIIM for 10% Off Self Decode * Use Code SIIM for a 10% Discount on the KAATSU Bands * Get Your Biomarkers Tested with Lets Get Checked At-Home Tests! Use Code SIIMLAND for a 20% Discount (sponsored)! * My New Book Stronger by Stress * My NEW BOOK Metabolic Autophagy * Metabolic Autophagy Audiobook * Metabolic Autophagy Master Class * Total Sleep Optimization Video Course * Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK * Get the Metabolic Autophagy Program * Keto Adaptation Manual Book * Watch the Biohacking Bootcamp Videos on Patreon * Body Mind Empowerment Handbook * Keto Fit Program * Keto // IF Program Stay Empowered Siim
57 min
Broken Brain with Dhru Purohit
Broken Brain with Dhru Purohit
Dhru Purohit
How to Prevent Cancer (Minisode #21)
For hundreds of years, cancer has been portrayed as a foreign invader we’ve been powerless to stop, but our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline, but the “War on Cancer” has hardly been won. Dhru’s guests on today’s mini-episode, Dr. Jason Fung and Dr. Elizabeth Boham, talk to us about the seed and soil analogy of cancer, and how the seed of cancer may exist in all of us, but the power to change the soil is in our hands. They also talk about how hyperinsulinemia may enable the development of cancer, and how we can build a soil that offers cancer a hostile environment as opposed to a fertile one. Dr. Jason Fung is a physician, author, and researcher. His groundbreaking science-based books about diabetes and obesity, The Diabetes Code, The Obesity Code, and The Complete Guide to Fasting have sold over one million copies. His latest book, The Cancer Code: A Revolutionary New Understanding of a Medical Mystery, was just released at the end of 2020.  Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The Ultrawellness Center in Lenox, MA. Through her practice and lecturing, she has helped thousands of people achieve their goals of optimum health and wellness. She is part of the faculty of the Institute for Functional Medicine and has been featured on the Dr. Oz show and in a variety of publications and media including Huffington Post, The Chalkboard Magazine, and Experience Life. Her DVD Breast Wellness: Tools to Prevent and Heal from Breast Cancer explores the Functional Medicine approach to keeping your breasts and whole body well.  Find Dhru’s full-length conversation with Dr. Jason Fung here: Find Dhru’s full-length conversation with Dr. Elizabeth Boham here: For more on Dhru Purohit, be sure to follow him on Instagram @dhrupurohit, on Facebook @dhruxpurohit, on Twitter @dhrupurohit, and on YouTube @dhrupurohit. You can also text Dhru at (302) 200-5643 or click here Interested in joining Dhru’s Broken Brain Podcast Facebook Community? Submit your request to join here: This episode is brought to you by the Pegan Shake. How you start your morning sets the tone for the day. I’m a huge fan of morning routines because I think they can transform your ability to focus, sleep well, and get the most out of your day, especially in this busy, modern world.  What I’ve found is that the best way to begin your day is to feed your body the right information or the right nutrients. That’s why Dhru and I created the Pegan Shake. It’s a nutritionally packed morning blend designed to support healthy blood sugar, energy, and brainpower.   It contains some of my most favorite brain-boosting foods like MCT and avocado. It also features acacia fiber for healthy gut function and collagen, pumpkin, and pea protein to support muscle synthesis. Check it out at See for privacy and opt-out information.
23 min
Finding Mastery
Finding Mastery
Dr. Michael Gervais
Jimmy Chin on Shifting Your Perspective of What's Possible
This week’s conversation is with Jimmy Chin, an Academy Award winning filmmaker, National Geographic photographer and professional mountain sports athlete. He has led or participated in cutting edge expeditions around the world for over 20 years. Jimmy has climbed and skied Mount Everest from the summit and made significant first ascents on all seven continents including the coveted first ascent of the Shark’s Fin on Mount Meru. For those of you unfamiliar with Meru, it’s the sacred five-peaked mountain of Hindu, Jain, and Buddhist cosmology and is considered to be the center of all the physical, metaphysical and spiritual universes. Jimmy’s photographs have graced numerous covers of National Geographic Magazine and the New York Times Magazine. He co-produces and co-directs with his wife Chai Vasarhelyi. Their film Meru won the Audience Award at the Sundance Film Festival in 2015 and was on the 2016 Oscar shortlist for Best Documentary Feature. Their latest documentary Free Solo, featuring Alex Honnold, won a BAFTA, seven primetime Emmys and the Academy Award for Best Documentary Feature in 2019. If you haven’t seen it, it’s the first thing you should watch after you’re done listening to this podcast. Jimmy’s resume precedes itself… I’d been wanting to have this conversation for a long time and I can’t wait for you to learn from him. We talk about his unorthodox path to becoming a photographer and filmmaker, chasing dreams, and managing risk.We also discuss why he almost turned down making “Free Solo” which I think you’ll find captivating… ----- Please support our partners! We're able to keep growing and creating content for YOU because of their support. We believe in their mission and would appreciate you supporting them in return!! To take advantage of deals from our partners, head to where you'll find all discount links and codes mentioned in the podcast.
1 hr 35 min
Plant Proof -  Evidence based nutrition
Plant Proof - Evidence based nutrition
Plant Based Nutrition & Inspirational Stories
Is grass-fed beef good for our planet?
In* Episode 116* I sit down with *Environmental Researcher Nicholas Carter* to talk further about grass-fed beef and planetary health. *Specifically we cover:* 1 - Results from a new peer-reviewed study on White Oaks Pasture, a farm that for years has claimed their beef is carbon negative. 2 - The importance of rewilding for cooling our planet 3 - How changing the foods we eat can help free up land to be rewilded and protect existing forests 4 - The GHG footprint of our food - how important is transport in this conversation? Beef versus Avocado as an example. 5 - The UK's Regenuary movement and some of their claims 6 - and much more *Resources:* * John Hokpkins University study published in 2020 which combined data from 140 countries and identified the single greatest way for someone to lower the GHG footprint of their diet was by adopting a vegan diet. Next best was a vegan diet with insects and molluscs and then a two-thirds vegan diet (2 vegan meals and snacks a day with one meal containing animal products). * You want to reduce the carbon footprint of your food? Focus on what you eat, not whether your food is local. Article by Hannah Ritchie * Author of White Oaks Pastures study acknowledging that their beef is NOT carbon negative and such claims are false. *My Book:* My book is coming out early 2021 published with Penguin - I cannot wait to share with you. In the lead up the launch I am going to share information about the title, cover, ways to win a copy, live event dates, free e-books etc. Register your email here so I can keep you up to date. *Want to support the show?* The single best way you can support the show is by leaving a review on Apple podcast app - it only takes a few minutes and would be much appreciated. Thanks in advance. *Simon Hill, Nutritionist, Sports Physiotherapist * Creator of and host of the Plant Proof Podcast Connect with me on Instagram and Twitter
1 hr 5 min
The Ultimate Health Podcast
The Ultimate Health Podcast
Jesse Chappus
389: Dave Asprey - Fast This Way to Burn Fat and Heal Inflammation
Dave Asprey (IG: @dave.asprey) is the Founder & Chairman of Bulletproof. He is a three-time New York Times bestselling science author, host of the Webby award-winning podcast Bulletproof Radio, and has been featured on the Today Show, CNN, The New York Times, Dr. Oz, and more. Today Dave is on the show for this 4th time to discuss his new book, Fast This Way: Burn Fat, Heal Inflammation, and Eat Like the High-Performing Human You Were Meant to Be. In this episode, we discuss: * Why Dave wrote Fast This Way * The biggest fasting hacks * What is grehlin? * Drinking coffee that makes you hungry? (it might be toxic) * The benefits of adding prebiotic fiber to your Bulletproof Coffee * Why Dave's not a fan of exogenous ketones * How to achieve metabolic flexibility * Don’t fall into the fasting trap * Women can start out fasting 3-4 days a week * The process of autophagy * The core definition of resilience * Intermittent fasting is a sustainable practice for helping prevent disease * The Four “F words” - Focus, Food, Fertility, & Friend * Fasting provides a sense of peace and power * The definition of biohacking in relation to intermittent fasting * The great debate - water vs. Bulletproof Coffee fasts * Coffee will give you better results during a fast * Dave’s profound experience with a Shaman * The difference between spiritual fasting and ayahuasca * Holotropic breathing can induce altered states * Why intermittent fasting matters * Dave’s experience coming back into society after water fasting * Is it safe for kids to fast? * Fasting for women * Activated charcoal is a magic supplement to add in while fasting * Taking serrapeptase during a fast Show sponsors: Organifi <== 20% off all Organifi products Paleovalley <== 15% off all Paleovalley products by using the code ultimatehealth at checkout Garden of Life <== Try Garden of Life's Dr. Formulated Probiotics Once Daily LMNT <== Get your free LMNT sample pack (8 packets) - all you pay is $5 for shipping (in the US) Related links: Dave Asprey - Fast This Way (book) Dave Asprey's website Bulletproof Follow Dave Asprey on Facebook, Instagram, and Twitter Dave Asprey - Super Human (book) Dave Asprey - Game Changers (book) Dave Asprey - Head Strong (book) Dave Asprey - The Bulletproof Diet (book) Listen to Dave Asprey previously on TUHP (episodes #061, #159, and #305) Bulletproof Coffee Bulletproof Brain Octane C8 MCT Oil Bulletproof InnerFuel Prebiotic Bulletproof Coconut Charcoal Gerald Pollack - The Fourth Phase of Water (book) Hans Krebs 40 Years of Zen Scott Barry Kaufman (books) Tim Ferriss - The 4 Hour Body (book) Related episodes: Gary Taubes – Are Carbs Making You Fat? (#387) 369: Dr. Jason Fung – Stop Snacking & Start Fasting 353: Dr. Satchin Panda – Time-Restricted Eating (TRE) & Managing Your Light Exposure 311: Leanne Vogel – Keto For Women, Loving Your Body, Sailing Through Life 294: Dr. Sara Gottfried – Brain Body Diet, Start To Surrender, Reset With Intermittent Fasting Note: Some of the links above are affiliate links. Making a purchase through these links won't cost you anything but we will receive a small commission. This is an easy, free way of supporting the podcast. Thank you! How can you support our podcast? 1. Apple users, please subscribe and review our show on Apple Podcasts, we make sure to read them all. Android users, be sure to subscribe to our show on Google Podcasts. Subscribers never miss any of the action ;) 2. Tell a friend about The Ultimate Health Podcast. They will surely thank you later. You can use the envelope button below to email a friend or tell them about TUHP in person. 3. Join TUHP Facebook community (FREE). This is where we all stay in touch and ask questions in between episodes. Join our community. 4. Follow our adventures on our favourite social media platform, Instagram. 5. Download The Ultimate Health Podcast app (FREE). This way you'll have our whole library of episodes right at your fingertips. Download our iOS/Apple app or our Android app. 6. Share using the buttons below. Thank you!
1 hr 26 min
Mastering Nutrition
Mastering Nutrition
Chris Masterjohn, PhD
MK-4 vs MK-7: Vitamin K2 Showdown | Masterjohn Q&A Files #189
Question: MK-4 vs MK-7: Vitamin K2 Showdown My default here is that a healthy diet would always have a mix of all of them. And although it's hard to justify a reason for having K1 specifically if you also have MK-7, the justification for having MK-4 is somewhat speculative. I wouldn't say speculative, but it's at kind of the theoretical level. So basically, MK-4 is not very good at supporting blood clotting, but MK-7 and K1 are. And we know that from human trials. And so we can at least say, you shouldn't only get MK-4, because it's not very good at supporting blood clotting. As default, get your K1 from veggies and then try to get a mix of MK-4 and MK-7, that totals up to 2-400 micrograms per day for the people who are just talking about one to 200 micrograms for general people, that can come from food if you eat those foods and supplement if you don't. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at and use the code QANDA to get 10% off the membership for life. From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at can sign up for a consultation at DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.
7 min
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