Isaiah 6 occurred early in his ministry, maybe chronologically before or immediately after chapter one.
Isaiah 6:1 Compare with 1:1.
2 Seraphim are spoken of only twice; both in this chapter. They are spiritual beings in the throne room of God. Similar to Ezekiel 1 and 10; Revelation 4
3 Revelation 4:8
5 Unclean lips - the context is that God commissions him to be His spokesman. Unclean lips are the manifestation of an unclean heart. Matthew 15:11-18
7 We cannot eliminate our iniquity; only God can.
John 14:10 The words that I say to you I do not speak on My own initiative, but the Father abiding in Me does His works.
8-9 Isaiah is a type for Jesus. John 4:34; 5:24, 30; 6:38, 39; 7:33; 9:4; 12:44; 13:20; and 16:5
8 “Here I am. Send me!” Isaiah 20:3
9-10 Many quotations and allusions are in the New Testament. The prophet Isaiah is quoted or referred to some eighty-five times in the New Testament. But several passages are cited or alluded to more than once, so that sixty-one separate passages are referred to in these eighty-five New Testament citations.
Matthew 13:14; Mark 4:12; Luke 8:10; John 12:40; Acts 28:26-27; Romans 11:8
Isaiah 6:10 There is a correlation between healing, humility, and sin.
53:4-5 Prophecy about Jesus
Genesis 20:17 The first healing in the Scriptures after he repented and made right what he did wrong--God healed him.
Exodus 15:26 If you obey, I will heal you.
Romans 10:9-ff vs 15 Isaiah 52:7; vs 16 Isaiah 53:1; vs 20 Isaiah 65:1; vs 21 Isaiah 65:2