Dive deep into the history of medicine to explore the origins of penicillin and the development of cephalosporins.  From the dank corners of Alexander Fleming's lab to the sewers of Sardinia we explore the history and controversy behind some of the most common antibiotics.  We will also discuss whether or not penicillin allergy is real and if you can give a penicillin allergic patient a cephalosporin and still keep your license to practice medicine.