This episode examines the history and development of nitroglycerin from volatile dynamite component to essential cardiac medication.  We examine the use of nitroglycerin in historic and modern times and its relevance as a cardiac medication in the post-PCI era.  We also dive deep into equivalent doses of nitro when given as a paste, drip, or tabs.  Finally, we look at the effective dose of nitro in several different conditions and explore whether or not there's any mortality benefit gained from nitro use.