Episode 29 COVID Vaccine Update Phase III Trials
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Every day is a new headline. Vaccine effective. When will we be over COVID. Exploding whale, ok, that last one isn't related. As far as the vaccine. We've talked about it previously, but today we're talking not just about the prospect of a COVID vaccine. We're talking about those that have developed phase 3 data. In this corner, Pfizer. In this corner, Moderna, Astrazeneca, Johnson and Johnson. How does it look? How interesting is it really? Is there a chance we may really see a light at the end of the tunnel? Should we be concerned? Join hosts Shanti and Danny as we talk with Dr. Bryan Simons and break down the most recent information about these vaccine trials and where we stand right now.


  1. Pfaender, S., et. al.; LY6E Impairs Coronavirus Fusion and Confers Immune Control of Viral Disease. Nature Microbiology. 23-Jul-2020. 5 (1330 - 1339). Doi: https://doi.org/10.1038/s41564-020-0769-y
  2. Langford, M., et. al.; Deletion of the Syncytin A receptor Ly6e Impairs Syncytiotrophoblast Fusion and Placental Morphogenesis Causing Embryonic Lethality in Mice. Scientific Reports. 02-Mar-2018. 8:3961 Doi: https://doi.org/10.1038/s41598-018-22040-2
  3. FDA; Vaccines and Related Biological Products Advisory Committee Meeting. FDA Briefing Document. 10-Dec-2020. https://www.fda.gov/media/144245/download
  4. Corum, J., Zimmer, C.; How the Pfizer-BioNTech Vaccine Works. The New York Times. 12-Dec-2020. https://www.nytimes.com/interactive/2020/health/pfizer-biontech-covid-19-vaccine.html
  5. Takebe, T., et. al.; The Current Status of Drug Discovery and Development as Originated in United STates Academia: The Influence of Industrial and Academic Collaboration on Drug Discovery and Development. Clinical Translational Science. 30-Jul-2018. 11:6 (597 - 606). Doi: https://doi.org/10.1111/cts.12577

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