FutureChain
FutureChain
Sep 30, 2020
Arnaud Deshais, Formerly of Novartis Vaccines and Diagnostics
Play • 1 hr 10 min

How to plan the production of an antigen and carry a vaccine through a cold chain.
What is an antigen and a cold chain 4:44. Production planning 20:15. Materials Requirements Planning 21:12. FDA has to approve sourcing of compounds 22:28. Trial process 23:12. Uncertainty of batch production process 28:19. Dealing with live materials 31:35. Production challenges 32:23. Determining quantity for clinical trials 34:30. Cost structure of drugs 35:35. Distribution network 37:14. Leveraging machine learning/AI, blockchain, RFID 42:36. Protecting patients 47:29. Maintaining strict temperature controls 50:17. Recall/reverse supply chain 52:30. Making sure opportunities to vaccinate are not missed through risk management 54:28. Theory of constraints 56:36. FDA can take over a factory 57:45. Weighing protecting patients against the demands for a vaccine in a pandemic 59:16. Timeline for a vaccine 1:00:30. Lean manufacturing 1:01:34. More inventory, more redundancies 1:04:18. Impacting people’s lives 1:05:36. Transparency and trust 1:06:58.

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