This is second part of the conversation with Randy Schekman. He is an investigator of the Howard Hughes Medical Institute and a Professor of Cell and Developmental Biology in the Department of Molecular and Cell Biology at the University of California at Berkeley. He was awarded the Nobel Prize in Physiology or Medicine in 2013 for his role in revealing the machinery that regulates the transport and secretion of proteins in our cells. He shares the prize with James E. Rothman of Yale University and Thomas C. Südhof of Stanford University.
In this conversation we talk about his work on scientific publishing, his suggestions for early-career researchers and his experience on Parkinson's project.
Listen to part I here: https://youtu.be/bl1uG4PbTOE
Find more about Randy's work: http://mcb.berkeley.edu/labs/schekman/
Randy's biography: https://www.nobelprize.org/prizes/medicine/2013/schekman/facts/
Episode links:
Website: https://www.reasonwithscience.com/home/the-noble-journey-with-randy-schekman-ii
Youtube: https://youtu.be/MNjfkoutAhQ
Spotify:
Apple podcast:
Google podcast:
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Apple podcast: https://podcasts.apple.com/us/podcast/reason-with-science/id1641776894
Google podcast: https://podcasts.google.com/feed/aHR0cHM6Ly9hbmNob3IuZm0vcy9iMjMyNDZlOC9wb2RjYXN0L3Jzcw
Timestamps:
00:00:00 Introduction
00:00:49 How to select a scientific question?
00:05:13 Bold ideas survive in science!
00:06:50 Importance of collaboration in science
00:12:24 ASAP project model for early career researchers
00:13:03 Change in the evaluation process
00:19:25 How to understand quality of science?
00:24:31 Parkinson's project (ASAP)
00:28:02 Why scientific publishing can change?
00:29:43 Understanding of scientific method to improve scientific publishing!
00:31:37 Any shift in pressure of publishing?
00:32:58 More about Parkinson's project (ASAP)
00:38:38 Role of unstructured proteins in neurodegenerative diseases
00:41:41 Unstructured proteins are the next problem!
00:42:38 No markers for Parkinson's so far!
00:43:50 Causes of Parkinson's
00:45:06 What can be a potential cure of Parkinson's?
00:47:12 Thank you!
More Talks from Randy:
TEDx on scientific publishing: https://youtu.be/-N4Mb8tsyT8
iBiology: https://youtu.be/xvjUgTKlKyU
Nobel prize inspiration initiative lecture: https://youtu.be/Udg6bYkBtX8
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