Genomics and the End of the Diagnostic Odyssey
Play episode · 21 min
Whole genome sequencing can help diagnose genetic diseases in days and holds the promise of helping parents avoid months or years of inconclusive tests. Listen to Dr. Vandana Shashi of Duke University and Kimberly LeBlanc of the Undiagnosed Diseases Network and learn how whole genome sequencing can short-circuit the diagnostic odyssey for patients with rare diseases.
DeepMind: The podcast
DeepMind: The podcast
DeepMind: The podcast
8: Demis Hassabis: The interview
In this special extended episode, Hannah Fry meets Demis Hassabis, the CEO and co-founder of DeepMind. She digs into his former life as a chess player, games designer and neuroscientist and explores how his love of chess helped him to get start-up funding, what drives him and his vision, and why AI keeps him up at night. If you have a question or feedback on the series, message us on Twitter (@DeepMindAI (https://twitter.com/deepmindai?lang=en) using the hashtag #DMpodcast) or emailing us at podcast@deepmind.com (mailto:podcast@deepmind.com) . Further reading: Wired: Inside DeepMind's epic mission to solve science's trickiest problem (https://www.wired.co.uk/article/deepmind-protein-folding) Quanta magazine: How Artificial Intelligence Is Changing Science (https://www.quantamagazine.org/how-artificial-intelligence-is-changing-science-20190311/) Demis Hassabis: A systems neuroscience approach to building AGI. Talk at the 2010 Singularity Summit (https://www.youtube.com/watch?v=Qgd3OK5DZWI) Demis Hassabis: The power of self-learning systems. Talk at MIT 2019 (https://cbmm.mit.edu/video/power-self-learning-systems) Demis Hassabis: Talk on Creativity and AI (https://www.youtube.com/watch?v=d-bvsJWmqlc) Financial Times: The mind in the machine: Demis Hassabis on artificial intelligence (2017) (https://www.ft.com/content/048f418c-2487-11e7-a34a-538b4cb30025) The Times: Interview with Demis Hassabis (https://www.thetimes.co.uk/article/demis-hassabis-interview-the-brains-behind-deepmind-on-the-future-of-artificial-intelligence-mzk0zhsp8) The Economist Babbage podcast: DeepMind Games (https://play.acast.com/s/theeconomistbabbage/99af5224-b955-4a3c-930c-91a68bfe6c88?autoplay=true) Interview with Demis Hassabis (https://storage.googleapis.com/deepmind-media/podcast/Game%20Changer%20-%20Demis%20Hassabis%20Interview.pdf) from the book Game Changer (https://www.newinchess.com/game-changer) , which also features an introduction from Demis Interviewees: Deepmind CEO and co-founder, Demis Hassabis Credits: Presenter: Hannah Fry Editor: David Prest Senior Producer: Louisa Field Producers: Amy Racs, Dan Hardoon Binaural Sound: Lucinda Mason-Brown Music composition: Eleni Shaw (with help from Sander Dieleman and WaveNet) Commissioned by DeepMind
37 min
Machine Learning Street Talk
Machine Learning Street Talk
Machine Learning Street Talk
Sara Hooker - The Hardware Lottery, Sparsity and Fairness
Dr. Tim Scarfe, Yannic Kilcher and Sayak Paul chat with Sara Hooker from the Google Brain team! We discuss her recent hardware lottery paper, pruning / sparsity, bias mitigation and intepretability.  The hardware lottery -- what causes inertia or friction in the marketplace of ideas? Is there a meritocracy of ideas or do the previous decisions we have made enslave us? Sara Hooker calls this a lottery because she feels that machine learning progress is entirely beholdant to the hardware and software landscape. Ideas succeed if they are compatible with the hardware and software at the time and also the existing inventions. The machine learning community is exceptional because the pace of innovation is fast and we operate largely in the open, this is largely because we don't build anything physical which is expensive, slow and the cost of being scooped is high. We get stuck in basins of attraction based on our technology decisions and it's expensive to jump outside of these basins. So is this story unique to hardware and AI algorithms or is it really just the story of all innovation? Every great innovation must wait for the right stepping stone to be in place before it can really happen. We are excited to bring you Sara Hooker to give her take.  YouTube version (including TOC): https://youtu.be/sQFxbQ7ade0 Show notes; https://drive.google.com/file/d/1S_rHnhaoVX4Nzx_8e3ESQq4uSswASNo7/view?usp=sharing Sara Hooker page; https://www.sarahooker.me
1 hr 31 min
Brain Science with Ginger Campbell, MD: Neuroscience for Everyone
Brain Science with Ginger Campbell, MD: Neuroscience for Everyone
Ginger Campbell, MD
BS 176 Seth Grant on Synapse Complexity
This is my fifth interview with molecular biologist and neuroscientist Dr. Seth Grant from The University of Edinburgh. Dr. Grant was recently recognized for his pioneering work by the Federation of European Neuroscientists. He continues to make fundamental discoveries about the structure and function of the synapse and this month we discuss the discovery that synapse complexity and diversity is greater than expected, along with the implications of these discoveries. Links and References: * Seth Grant: University of Edinburgh * FENS EJN Award 2020 * Cizeron M, Qiu Z, Koniaris B, et al. A brainwide atlas of synapses across the mouse life span. Science. 2020;369(6501):270-275. doi:10.1126/science.aba3163 * Please visit http://brainsciencepodcast.com for additonal references and episode transcripts. Please Visit Our Sponsors: * GreenChef: at http://greenchef.com/ginger80 * TextExpander at http://textexpander.com/podcast Announcements: * Coming November 17, 2020: Webinar: "Embracing Uncertainty: How to Thrive in Uncertain Times." Listen to closing announcements to learn more. * Coming soon! episode compilations based on topic or guest. Look for all Seth Grant's interview next month. * _Brain Science_ comes out on 4th Friday each month. * Support Brain Science by buying Are You Sure? The Unconscious Origins of Certainty by Virginia "Ginger" Campbell, MD * Learn more ways to support Brain Science at http://brainsciencepodcast.com/donations * Sign up for the free Brain Science Newsletter to get show notes automatically every month. You can also text brainscience to 55444 to sign up. * Check out the free Brain Science Mobile app for iOS, Android, and Windows. (It's a great way to get both new episodes and premium content.) * Send email to brainsciencepodcast@gmail.com or post voice feedback at http://speakpipe.com/docartemis. Connect on Social Media: * Twitter: @_docartemis_ * Facebook page: _http://www.facebook.com/brainsciencepodcast_ Contact Dr. Campbell: * Email: brainsciencepodcast@gmail.com * Voicemail: _http://speakpipe.com/docartemis_
1 hr 27 min
Materialism
Materialism
Taylor Sparks and Andrew Falkowski
μ: When Materials Failure Leads to Wildfire
When you hear of massive wildfires you probably think of the usual suspects: lightning, a campfire carelessly left unattended, maybe a cigarette butt thrown from a vehicle? What you probably don't think of is materials fatigue of a steel hook. This micro episode centers on the story of the Camp Fire in Butte County, California that took 85 lives, decimated the land, and was the biggest insured disaster that year. A look at what mistakes PG&E made ranging from their lack of records keeping to materials incompatibility and testing methods that led to the deadliest fire in California's recorded history. References: https://twitter.com/TubeTimeUS/status/1306359385656946688 https://www.electricaleasy.com/2016/10/insulators-used-in-overhead-power-lines.html https://doi.org/10.1016/j.ijfatigue.2004.01.004 If you have questions or feedback please send us emails at materialism.podcast@gmail.com. Make sure to subscribe to the show on iTunes, Spotify, google play, and now Youtube or wherever you find your podcasts. If you like the show and want to help us reach more people, consider leaving a review - it helps us improve and it exposes new people to the show. Finally, check out our Instagram page @materialism.podcast and connect with us to let us know what new material you’d like to hear about next. We’d like to give a shoutout to AlphaBot for allowing us to use his music within the podcast. Check him out on Spotify. And as always a special thanks to Kolobyte who created the intro and outro for our podcast. He makes a ton of really cool synthwave music which you can check out at kolobyte.bandcamp.com. Also visit our sponsors for this episode The American Ceramic Society Arts Archeology & Conservation Science division, www.materialstoday.com, and matmatch.com. Follow us on Instagram: https://www.instagram.com/materialism.podcast/?hl=en Follow us on Twitter: https://twitter.com/MaterialismPod Visit our website: www.materialismpodcast.com Materialism Team: Taylor Sparks (co-creator, co-host, production), Andrew Falkowski (co-creator, co-host, production), Jared Duffy (production, marketing, and editing) Support Materialism by donating to their Tip Jar: https://tips.pinecast.com/jar/materialism
13 min
Making Positive Psychology Work Podcast
Making Positive Psychology Work Podcast
Michelle McQuaid
3 Ways To Make Your Workplace More Human-Centered - with Michele Zanini
Michele Zanini is the co-founder of the Management Lab, with the wonderful Gary Hamel where they help forward-thinking organizations become more resilient, innovative, and engaging places to work. Together, they recently wrote the bestselling book, Humanocracy, creating organizations, as amazing people inside of them, and their work is featured in the Harvard Business Review, the Financial Times, and The Wall Street Journal. In this week’s episode, we explore the simple steps we can each take to make our workplaces more human-centered and less bureaucratic. Connect with Michele Zanini: * https://hackmyorg.humanocracy.com/welcome You’ll Learn: * [04:33] - Michele explains what studies are finding about the value of embedding humanity over bureaucracy when it comes to caring for worker’s wellbeing and improving performance. * [11:16] - Michele offers some practical steps teams can take to move towards a more human-centric approach to working together. * [17:06] - Michele explains how you can create a movement in your workplace to be more human-centered. * [20:45] - Michele explains how leaders can help enable change activists across their workplace. * [25:03] - Michele enters the lightning round. Your Resources: * MPPW Podcast on Facebook Group * The Age of Heretics by Art Kleiner * Humanocracy by Gary Hamel & Michelle Zanini Thanks for listening! Thanks so much for joining me again this week. If you enjoyed this episode, please share it using the social media buttons you see at the bottom of this post. Please leave an honest review of the Making Positive Psychology Work Podcast on iTunes. Ratings and reviews are extremely helpful and greatly appreciated. They do matter in the rankings of the show, and I read each and every one of them. And don’t forget to subscribe to the show on iTunes to get automatic updates. It’s free! You can also listen to all the episodes of Making Positive Psychology Work streamed directly to your smartphone or iPad through stitcher. No need for downloading or syncing. Until next time, take care! Thank you, Michele!
31 min
Learning Bayesian Statistics
Learning Bayesian Statistics
Alexandre ANDORRA
#25 Bayesian Stats in Football Analytics, with Kevin Minkus
Have you watched the series « The English Game », on Netflix? Well, I think you should — it’s a fascinating dive into how football went from an aristocratic to a popular sport in the late 19th century England. Today it is so popular that it became a valuable business to do statistics on the game and its players! To talk about that, I invited Kevin Minkus on the show — he’s a data scientist and soccer fan living in Philadelphia. Kevin’s currently working at Monetate on ecommerce problems, and prior to Monetate he worked on property and casualty insurance pricing. He spends a lot of his spare time working on problems in football analytics and is a contributor at American Soccer Analysis, a website and podcast dedicated to… football made or played in the US (or “soccer”, as they say over there). Kevin is responsible for some of their data management and devops, and he recently wrote a guide to football analytics for the Major League Soccer’s website, entitled « Soccer Analytics 101 ». To be honest, I had a great time talking for one hour about two of my passions — football and stats! Soooo, maybe 2020 isn’t that bad after all… Ow, and beyond football, Kevin is also into the digital humanities, web development, 3D animation, machine learning, and… the bassoon! Our theme music is « Good Bayesian », by Baba Brinkman (feat MC Lars and Mega Ran). Check out his awesome work at https://bababrinkman.com/ ! Links from the show: * Kevin on Twitter: https://twitter.com/kevinminkus * Kevin on GitHub: https://github.com/kcm30 * Soccer Analytics 101: https://www.mlssoccer.com/soccer-analytics-guide/2020/soccer-analytics-101 * American Soccer Analysis: https://www.americansocceranalysis.com/ --- Send in a voice message: https://anchor.fm/learn-bayes-stats/message
56 min
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