Episode 463: The COVID-19 vaccine – all the numbers so far and much more
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In episode 463, James and Mike talk about the latest reports of the results of the 2 COVID-19 vaccine trials. We give you all the numbers you need to know and maybe more importantly we discuss the nuances around industry bias, the approval process and general thoughts around vaccines in these crazy times.
Show notes
Stimulus.
Stimulus.
Rob Orman, MD
38. How to Meditate
Master meditation teacher Robert Beatty walks us through: the basics of meditation, how to start a meditation practice, principles of mindfulness, understating the roots of suffering, how concentrating on the breath can lead to insight, and healthy vs unhealthy coping. Listen on: * iTunes * Spotify * Stitcher Guest Bio: Robert Beatty is co-author of Mindfulness for a Happy Life as well as founder and guiding teacher of the Portland Insight Meditation Community. He has worked with thousands of students and, as a practicing therapist, has created a unique synthesis of Buddhist methods of awakening and healing and those of western psychotherapy. Episode Sponsor: Today’s episode is sponsored by Stages Cycling, makers of industry leading cycling computers, power meters, heart rate monitors, and indoor studio bikes. When I say industry leading I’m talking about last year's Tour de France winner Tadej Pogacar uses a Stages power meter and cycling computer. They are legit! Stimulus listeners get 20% off your order of all Stages outdoor products (excepting the SB20 Smartbike which is awesome, just no discount). Use this link to go to Stagescycling.com and your 20% discount will be applied at checkout. We discuss: * When starting a meditation practice, the importance of knowing what your ‘fantasy’ is about meditation [06:50]; * Why having a meditation teacher is essential and how Ruth Denison influenced Beatty’s practice [08:30]; * The paradox of 2 truths: skillful effort to restrain unwholesome mental states and the effort to bring into being wholesome mental states [12:30]; * Beatty’s guided meditation for the novice [15:00]; * What it is in mindfulness that we’re actually being mindful of [25:10]; * Driving a car The Headless Way [28:50]; * Why it is almost universal in meditation practices to use the breath as the primary meditation object [30:15]; * Beatty’s opinion of meditation apps [35:37]; * How intentionally letting go of your thoughts and concentrating on your breath can lead to deep insight [38:38]; * The 3 characteristics of existence and how they provide spiritual insight [42:30]; * Using meditation as a purification process to help you let go of stuff (or people) that cause negative emotions [48:50]; * A skillful way to come back to your meditation object that is not self-criticizing [51:30]; * The metaphor of the two arrows and how it can be applied in daily life [54:50]; * Healthy vs. unhealthy coping mechanisms [01:00:00]; * The reasons people come to meditation [01:06:00]; * Beatty’s aspirations [01:09:30]; * Why ‘should’ is such a violent word [01:10:00]; * And more. For complete and detailed show notes, previous episodes, or to sign up for our newsletter: https://www.stimuluspodcast.com/ If you like what you hear on Stimulus and use Apple/iTunes as your podcatcher, please consider leaving a review of the show. I read all the reviews and, more importantly, so do potential guests. Thanks in advance! Interested in sponsoring this podcast? Connect with us here Follow Rob: Twitter: https://twitter.com/emergencypdx Facebook: https://www.facebook.com/stimuluswithrobormanmd Youtube: https://www.youtube.com/c/emergencypdx
1 hr 13 min
Freely Filtered, a NephJC Podcast
Freely Filtered, a NephJC Podcast
NephJC Team
Freely Filtered 028: Finerenone for diabetic kidney disease
The Filtrate: Swapnil Hiremath Samira Farouk Matt Sparks Joel Topf Jennie Lin And two special guests: Katherine Tuttle Clinical Professor Division of Nephrology, Medical & Scientific Director, Providence Medical Research Center/Sacred Heart Center, Professor of Basic Medical Sciences, WWAMI Program Washington State Universityendocrinologist and nephrologist at the University of Washington Ian de Boer Professor in the Division of Nephrology, Adjunct Professor, Epidemiology and Associate Director, Kidney Research Institute Show Notes: The Guideline NephJC’s summary Accord study showing harm from tight glycemic control Advance Trial the other trial showing harm from tight glycemic control 2007 KDOQI diabetes guidelines 2012 KDOQI diabetes guidelines ADA guidelines Rob Nelson, diabetes legend Classic pathology of diabetic nephropathy Should all patients with diabetes have a kidney biopsy? Flow trial: A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease The Grading of Recommendations Assessment, Development and Evaluation (short GRADE) working group. Don’t you love it when the first word in an acronym is the acronym itself. Continuous Glucose Monitoring and Use of Alternative Markers To Assess Glycemia in Chronic Kidney Disease Continuous glucose monitoring and icodextrin. Keto diets have 1.2 to 1.7 g protein/kg Urinary Sodium and Potassium Excretion, Mortality, and Cardiovascular Events by the PURE investigators The Association Between Kidney Disease and Diabetes Remission in Bariatric Surgery Patients With Type 2 Diabetes Jordy Cohen and Bariatric surgery in CKD at Kidney Week Metformin knocking out of the park in UKPDS Kidneys at the Zoo: What Can We Learn from Comparative Renal Physiology? at Kidney Week
1 hr 2 min
Bedside Rounds
Bedside Rounds
Adam Rodman, MD, MPH, FACP
60 - Santa's Salmonella
For a special holiday treat, we’re going to explore two tales of salmonella disease detectives -- the first about Mary Mallon (“Typhoid Mary”) and the birth of the genre; and the second about a mysterious salmonella outbreak at Massachusetts General Hospital solved with the assistance of a very jolly patient. Along the way, we’ll talk about clinical epidemiology, the long-lasting influence of Berton Roueché, and the joys of being an internist! You can sign up for the Digital Education conference at cmeregistration.hms.harvard.edu/digitaleducation. Sources: * Buckle GC, Fischer Walker CL, and Black RE, Typhoid fever and paratyphoid fever: Systematic review to estimate global morbidity and mortality for 2010.J Glob Health. 2012 Jun; 2(1): 010401. * Marineli F et al, Mary Mallon (1869-1938) and the history of typhoid fever.Ann Gastroenterol. 2013; 26(2): 132–134. * Soper GA, The Curious Career of Typhoid Mary, read on May 10, 1939 before the Section of Historical and Cultural Medicine. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1911442/pdf/bullnyacadmed00595-0063.pdf * Norrington B, Cochineal: A Little Insect Goes a Long Way, UCSB Geography. * Roueche B, The Santa Claus Culture, The New Yorker, Aug 27, 1971. * Lang DJ et al, Carmine as a Source of Nosocomial Salmonellosis, NEJM. Apr 13, 1967. * You can buy Medical Detectives here: https://www.amazon.com/Medical-Detectives-Collection-Award-Winning-Investigative/dp/0452265886
38 min
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