Insulin resistance from fat invading muscle cells? | Masterjohn Q&A Files #181
Play • 7 min

Question: Insulin resistance from fat invading muscle cells?I think increased free fatty acids in the blood. That's going to be a normal reaction to dietary fat and I think that if you have increased fatty acids than increased glucose, that you have more energy to dispose off. And if you have more energy to dispose of, and you don't dispose off the energy, then that's going to cause insulin resistance.If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

From now through March, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Siim Land Podcast
Siim Land Podcast
Siim Land
#229 Becoming Antifragile During Times of Chaos - Siim Land on Filip Van Houte's Podcast
This is a replay of Siim Land on Filip Van Houte's podcast Human Rants. Timestamps: * 00:55 Comments on World Events * 07:30 How Legislative Organizations Make Decisions * 11:00 How to Recognize Bad Advice * 15:30 Getting Stuck in Tribal Politics * 19:07 How to Not Get Addicted to Social Media * 24:34 How to Allow Spontaneity * 27:50 Future of Technology and Humans * 31:46 Technology Regulating Human Behavior * 37:37 Antifragility and Civilization * 45:25 Best Supplements People Need * 52:00 Aging and Chronic Diseases And much more Here are the links to the podcast on all platforms * Link to the Audio Podcast on iTunes and Stitcher * Link to the podcast on Spotify * Link to the podcast on CastBox * Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body. With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That’s an AMAZING value. And I promise that deal is ONLY available on this specific website, Click Here to Support the Show on Patreon! Show Notes * Filip Van Heute YouTube Channel * Stronger by Stress on Amazon * Stronger by Stress Audiobook * The Immunity Fix on Amazon * Get Magnesium Breakthrough for a 10% Discount! * Black Stuff Fulvic Acid 15% OFF with the Code SIIM * Use Code SIIM for 10% Off Self Decode * Use Code SIIM for a 10% Discount on the KAATSU Bands * Get Your Biomarkers Tested with Lets Get Checked At-Home Tests! Use Code SIIMLAND for a 20% Discount (sponsored)! * My New Book Stronger by Stress * My NEW BOOK Metabolic Autophagy * Metabolic Autophagy Audiobook * Metabolic Autophagy Master Class * Total Sleep Optimization Video Course * Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK * Get the Metabolic Autophagy Program * Keto Adaptation Manual Book * Watch the Biohacking Bootcamp Videos on Patreon * Body Mind Empowerment Handbook * Keto Fit Program * Keto // IF Program Stay Empowered Siim
1 hr 1 min
Peak Human - Unbiased Nutrition Info for Optimum Health, Fitness & Living
Peak Human - Unbiased Nutrition Info for Optimum Health, Fitness & Living
Brian Sanders - Filmmaker of Food Lies & Health Coach
Part 115 - Dr. Cate Shanahan & Tucker Goodrich on the True Cause of Disease and How We Know This
Today is a special show that I really enjoyed with 2 guests - Dr. Cate Shanahan and Tucker Goodrich. I had Tucker on years ago for episode 20 and he laid out the entire case against seed oils which was very compelling. Dr. Cate has been on twice already (more recently) and is a wealth of knowledge on many, many things, especially the dangers of seed oils and reinforcing the Sapien diet concepts. We cover how people get fat & sick all the way down to the mitochondrial level. We discuss the different players in this process including seed oils (or more specifically excess amounts of omega-6), refined grains, and sugar. We also do my favorite thing and look at all sides of the arguments. We use an article a seed oil supporter wrote as a tool to check in on the studies and claims cited. You won’t want to miss this one! It’s a long one, but we cover a lot, and there’s a bunch of great new info. This podcast is made possible by my company Nose to Tail where we offer nutrient dense, whole foods delivered to you. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org SHOW NOTES: * [11:40] Are seed oils the ultimate cause of chronic disease? * [20:00] PUFAs, hyperglycemia, and liver damage. * [22:00] Difference between omega-6 and 3 fatty acids. * [23:40] PUFAs, inflammation, and damage to the thyroid. * [32:00] Diseases of Civilizations and PUFA consumption. * [38:00] The importance of consuming healthy fats. * [41:30] Seed oils can lead to overeating, mitochondrial dysfunction, and eventually even heart failure. * https://journals.physiology.org/doi/full/10.1152/ajpheart.00480.2004 * [54:30] The connection between the American Heart Association and seed oil industry. * [1:04:00] Counter arguments for studies that support seed oils. * https://www.alineanutrition.com/2020/09/26/of-rats-and-sydney-diet-heart-drawing-a-line-under-polyunsaturated-pseudoscience/ * [1:29:00] Monocultures, monocropping, and the need for regenerative agriculture. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg
1 hr 53 min
The Healthy Rebellion Radio
The Healthy Rebellion Radio
Robb Wolf
Hormone Replacement, Potassium and Metabolic Disorders, Toenail Fungus | THRR066
Potassium Intake As It Relates To Insulin Resistance, Metabolic Disorders And NAFLD; Hormone Replacement Therapy - Good? Bad?; Toenail Fungus; High BUN: Should I Be Concerned?; Where In The World To Live? Make your health an act of rebellion. Join The Healthy Rebellion Please Subscribe and Review: Apple Podcasts | RSS Submit your questions for the podcast here Show Notes: News topic du jour: Green tea extract only affects markers of oxidative status postprandially: lasting antioxidant effect of flavonoid-free diet* In conclusion, GTE incorporated into meat patties in doses realistic for addition to processed foods only leads to a short-term change in plasma antioxidant capacity and has no long-term effects on oxidation parameters within the blood or urine compartments in smokers or in non-smokers. The study can therefore be seen as a 10 weeks controlled study with dietary depletion of all food antioxidants derived from fruits and vegetables, except for carrots and potatoes. During the depletion we observed a decrease in oxidative damage to proteins, DNA, and lipids, concomitantly with a major reduction in plasma ascorbate and minor changes in other vitamins and in anti- oxidant enzyme activities. We speculate that these seem- ingly positive effects on oxidative status are partly due to depletion of some pro-oxidant compounds co-existing with vitamin C in fruits and vegetables and this underlines the general lack of solid knowledge of the mechanisms by which a diet rich in fruits and vegetables cause a decrease in the risk of chronic diseases. 1. Potassium intake as it relates to Insulin resistance, metabolic disorders and NAFLD [22:41] Deirdre says: Hi Robb, I stumbled upon a couple of journals that state there is a link between hypokalemia and IR, metabolic disorders and NAFLD, of which I have (all of them). I have a difficult time losing weight, even when following healthy eating to a T. I've been tracking my food on myfitnesspal for a month, and upon reflection, I'm not getting NEARLY enough potassium every day. Sodium doesn't seem to be an issue. I salt my food pretty well. I do magnesium soaks once or twice a week. Can you touch on this subject a bit more, and maybe make some recommendations on how to hit that 4700 mg mark for potassium daily? Even with eating a large amount of veggies and protein, it's still a difficult number to hit. Dried herbs like chervil, parsley, basil and tarragon seem to be my best bets, but it's difficult to get 100g of dried herbs in a day. LOL. Thanks, Deidre 1/2lb steak 800mg 1 avocado 1,000mg 1oz nuts 200mg 2. Hormone Replacement Therapy - Good? Bad? [27:22] Marianna says: I'm a 69 YO. I'm a post menopausal female, who a little over a year ago started HRT about 18 months ago. I used bio identical HRT for the first 7 years after menopause then in keeping with recommendations went off it for about 11 years. My goal in retirement is to be as mentally and physically healthy as possible for as long as I possibly can. I'm quite active, exercise daily including cardio and strength training with yoga thrown in. Through IF and low carb eating I've recently lost 25 pounds and am5'6" and 155 lbs. The HRT I 'm using is administered via bio identical pellets every 4th month with oral progesterone taken daily. My decision to go back to HRT was prompted by reading Avrum Blooming's book Estrogen Matters. It was recently reinforced by reading Lisa Mosconi's book The XX Brain. Now finally to my question! Am I doing myself harm or good or just wasting my money (I can afford it) by seeking HRT at my age? As far as noticeable health benefits the main thing I notice is my skin looks a lot better. Effect of menopausal hormone therapy on components of the metabolic syndrome 3. Toenail fungus [31:52] Bradley says: Hello Robb and Nicki, About a year ago the middle toe toenail on my left foot curled on the right side of the toe and I noticed there was fungus under the toenail. There was no pain and did not seem to be a problem. During this past summer, I went to the doctor for my regular annual blood draw and showed the doc the toenail. She said it is just cosmetic and is not an issue unless it spreads. Also, she said the only thing that can be done is take some pills, which she said is very hard on the liver, for several months until it clears, and recommended that I do not take the medication unless the fungus spreads. Then, in October/November, I noticed fungus behind the big toe toenail on my right foot. The toenail on my right foot did not curl, but, it has more of a lumpy feel and I can see the white fungus growth underneath the toenail. I still have zero pain on either foot and not sure if it is even a big concern. However, considering a conventional doctor is reluctant to put me on the medication because of the potential side effects, do you happen to know of anything else that can be done? I have tried the foot baths with tea tree oil and other foot soaks and toenail ointments and they are not working. I have found some docs on the internet recommending special diets for around 6 months or more, but they all vary somewhat (have not attempted yet). Also, found a somewhat fringe treatment by ingesting sugar and turpentine (have not tried this either). Supposedly, the sugar attracts the parasite or fungus or whatever and the turpentine eliminates it and you just shit it all out. Thank you both very much. 4. High BUN: should I be concerned? [39:07] William says: Hi Robb and Nicki, Over 5 years of taking annual bloodwork, I have found that my BUN is consistently high (30-35 mg/dL). I’ve had my own theories as to why, so see if am I on the right track with this line of thinking: 1. I’ve been a daily sauna user for the past 5 years, which could lead to dehydration and elevated urea in the blood. I drink at least a liter of water during and after, and probably an additional 1-2 L around dinner time. Total daily liquids averages 4-5L. I salt my food heavily and take Mg and K supplements, but don’t measure total electrolytes 2. I tend to eat most of my protein at night (100-150g), with a half coming in the form of plant-based protein powders 3. The blood tests are always taken first thing in the morning, so it’s possible I’m still dehydrated from the night’s of sleep, combined with the high protein intake. I don’t normally drink a lot of water upon waking because I don’t feel thirsty, although thanks to LMNT I’m starting to change that :-) My doctor is concerned about my high BUN and an increase in chance to develop gout and kidney damage. He has advised me to reduce my protein intake. However, my avg daily protein is 150g, and as an active 165lb man, that number seems safe and appropriate. Have you looked much into BUN in people on paleo/keto diets with high protein? Are my numbers way out of whack and dangerous? Or is high BUN less of a concern in the context of a clean diet and low systemic inflammation? Could there be something else going on to contribute to this consistently high BUN? Or is it as simple is spreading my protein intake more evenly throughout the day instead of one large bolus at night? Any thoughts and insights you have would be very helpful! Thanks! William 5. Where In The World to Live? [44:24] Keri says: Hi guys! Huge fan since way back in the day. Love the podcast and am grateful for all you do. I have a weird, possibly not typical question, but value your opinions and feel like it’s relevant and something you might have an opinion on. Anyway... My family has been working towards moving to a small, debt-free, self-sufficient farm since 2009. We’re currently ready to start looking to buy. We grew up on farms/ranches and have years of experience. We’re into regenerative agriculture, pasture raised animals etc. We also homeschool all of our kids. My question is: we can move anywhere, considering political climates, taxes, cultural/social environment,…
50 min
The Keto Kamp Podcast With Ben Azadi
The Keto Kamp Podcast With Ben Azadi
Ben Azadi
Dr Jeff Matheson | Why the quality of your fats on keto matter! KKP: 237
Today, I am blessed to have here with me for the THIRD time Dr. Jeff Matheson. He is the co-founder of an all-natural migraine and headache centre, which promotes a non-narcotic approach to pain and headache management. Plus, Dr. Jeff Matheson is the co-founder and medical director of Pure Life Science. Dr. Jeff Matheson successfully practiced medicine in emergency departments across Canada and internationally, from Ontario, Newfoundland, and Abu Dhabi in the United Arab Emirates. He later was appointed Medical Director of Med-EmergInc in 1998, a company dedicated to staffing underserved hospitals in Canada. Dr. Matheson has traveled extensively throughout Europe, the Middle East, Africa, and South East Asia and well as Oceania. According to Dr. Matheson, “traveling is the best education!” Dr. Matheson is an enthusiastic believer, as well as being immersed in other cultures. Similarly, if one does not listen to patients, one won’t hear what is necessary to understand the patient’s problem, i.e., the patient’s “culture.” It is with this ability to listen and empathize with the patients that Dr. Matheson allows an accurate diagnosis and develop sustainable solutions, optimizing health, and patient outcomes. If a solution cannot be determined, resources will be dedicated, through the involvement of alternative care specialists, ascertaining the best possible treatment for the patient by trying to treat causes, not just manage symptoms. In this episode, Dr. Jeff Matheson dives straight into how our body will produce energy through our cell membranes. If someone lacks energy, they usually think they have a hormone problem, meaning they need to take more hormones. However, that's not the case. Dr. Jeff Matheson explains how our hormones require a delicate balance; adding exogenous hormones will push our bodies out of balance. Instead, think about making different nutritional decisions to fix any hormone irregularities. Later, we discuss why keto and fasting are great for our cells and why fish oils aren't so great for them. Tune in as we chat all about Pure Life Omegas. * Pure Form Omega: https://purelifescience.com/products/pure-form-omega-natural (Use code: Ben4) * Pure Form Omega Liquid: https://purelifescience.com/products/pure-form-omega-liquid (Use code: Ben3) [01:15] How Our Body Will Produce Energy * We're made up of about 70 trillion cells. * Our body is great at communication, not only within each organ but between organs. All this communication is done through the cell membranes. * The cell membrane is the basic divide between the outside world and the inside world – that’s where the fundamental communication takes place. * All hormonal issues boil down to unhealthy cell membranes. [03:45] Hormones Aren’t That Simple * Hormones need a delicate balance. If you start adding exogenous hormones into the system, you're going to push that system out of balance. * How adding exogenous hormones into your body will affect you later on down the road is really difficult to predict. * The whole hormonal cascade is extremely complex. * When people correct their underlying nutritional issues, usually within six to nine months, they should be able to come off all exogenous hormones. [06:25] Bad Things That Develop In Our Cells * The problem that will affect people first is mitochondrial issues. The mitochondria is a very high-energy place, it's supposed to produce lots of energy, but it can be screwed up fairly easily. The first thing that people feel is fatigue - that's that mitochondria sort of breaking down. * Later down the road, genetic issues will show up, and that’s when you start getting cancers. [09:15] Why Your Supplements Might Not Be Working * If you have an unhealthy cell membrane, things can't get in. * On average, the cell membrane is 50% fat. If you have abnormal fats in that cell membrane, that membrane becomes more like plastic. When you put plastic wrap on something, not a lot of stuff gets through. * So, you won't be able to get good things in very efficiently, and you won't be able to get the bad things out very efficiently. It's only a matter of time in that kind of situation until you have a total cell breakdown. [14:30] How Keto & Fasting Help Support The Cell Membrane * The brain is about 70% fat – it operates on keto about seven to eleven times more efficiently than on carbohydrates. * Fat-based energy production is way more efficient. * Every single one of our ancestors did keto because their environment forced them into it. * Once you achieve metabolic freedom and flexibility, your body can actually manufacture glucose from the fat and from protein. [18:20] Is Omega-6 Bad For You? * Omega-6 isn’t bad for you; processed omega-6 is bad for you. * Omega-6 has the same oxygen-binding capacity as hemoglobin. Hemoglobin is also intimately bound to the cell membrane; so, they work well together. * After people take the proper amount of omega-6, they feel better. Plus, they will be able to feel it fast. [21:10] The Issue With Fish Oil * Fish oil is high in EPA and DHA. They're what we call unsaturated are much more unstable. * Not only is fish oil too unstable for us, it's not really needed in very large quantities. * As it turns out, the brain only uses about seven and a half milligrams per day of EPA and DHA. * People on a high dose of fish oil will have a problem with nose bleeds – it’s an obvious example of fluidity. * If you overload yourself with fish oil, the mitochondria is only half as efficient as it should be. [34:55] Is Eating Fish Bad Too? * You can certainly eat fish. When you cook it, you're destroying the fats anyways. * It's the deepwater fish that are higher in EPA and DHA. * Fish have a lot of good nutrition in it unless it's been contaminated with heavy metals and stuff. In Japan, where they eat mostly raw fish, they do have higher rates of hemorrhagic strokes. * Fish that have fewer heavy metals are ones with a fast turnover like sardines. Tuna is a bad one because tuna will eat a lot of other fish and is lower on the food chain. [39:45] About Pure Form * Pure Form Omega® Natural is an organic, plant-based, fish-free, cold-pressed, source of omega-6 and omega-3 essential fatty acids. * It has been processed in a way that retains all the functions of the fat. * It is a proprietary formulation made up of primrose oil, sunflower seed oil, pumpkin seed oil, and organic extra virgin coconut oil. These are all excellent sources of essential omega-6, along with organic flaxseed oil for essential omega-3, to obtain what we consider the ideal omega 3-6 combination. [45:25] Good vs. Bad Sunflower Oil * If you look at the average sunflower oil, even organic sunflower oil that's on the shelf, it's not cold-pressed. Heat and oxygen are bad for fats. * When you do cold pressure, you actually lose about 20% of the oil. * You can put a processed oil on the shelf for years; it'll look the same. [51:20] Hangover Prevention * Since the brain is 70% fat, you put all the good fats in the brain, you don't get headaches. * Just another reason to love Pure Form Omega®. * However, most people will feel a little tired the next day because alcohol disturbs your sleep pattern. Luckily, you won't have the headache and all the other stuff that accompanies those hangovers. AND MUCH MORE! Resources from this episode: * Check out Pure Life Science: https://purelifescience.com/ (Use code Ben4 for the bottles and Ben3 for the liquids). * Email Jeff@PureFormOmega.com: Jeff@PureFormOmega.com * Follow Dr. Jeff * Twitter: https://twitter.com/jeffmdcare * Listen to How Much Fish Oil Is Too Much? Research on Fish Oil With Dr. Jeff Matheson: KKP 75: https://podcasts.apple.com/us/podcast/how-much-fish-oil-is-too-much-research-on-fish-oil/id1470779784?i=1000460552814 * Watch Dr. Jeff Matheson, Cell Membrane S…
59 min
Fast Keto with Ketogenic Girl
Fast Keto with Ketogenic Girl
Vanessa Spina
The Metabolism Boosting Benefits of Diet Breaks!
Hi friends! This episode is all about The Metabolism Boosting Benefits of Diet Breaks! Get Your FREE ebook on keto: ketogenicgirl.com/pages/free-ebook Try the 28 Day Ketogenic Girl Challenge: ketogenicgirl.com Special thank you to our Fast Keto sponsors: Unlock Your Body's Data using a Nutrisense Continuous Glucose Monitor (CGM)! Analyze how your body responds to food, exercise, stress, and sleep in real-time. Visit Nutrisense.io and use the code KetogenicGirl for $25 off YOUR first month! - For a limited time, new members can get TWO New York Strip steaks and one pack of bacon when you sign up for ButcherBox by going to https://butcherbox.com/fastketo. That’s https://www.butcherbox.com/fastketo to get TWO New York Strip steaks and one pack of bacon in your first order! - Prior to beginning a ketogenic diet you should undergo a health screening with your physician to confirm that a ketogenic diet is suitable for you and to rule out any conditions and contraindications that may pose risks or are incompatible with a ketogenic diet[, including by way of example: conditions affecting the kidneys, liver or pancreas; muscular dystrophy; pregnancy; breast-feeding; being underweight; eating disorders; any health condition that requires a special diet [other conditions or contraindications]; hypoglycemia; or type 1 diabetes. A ketogenic diet may or may not be appropriate if you have type 2 diabetes, so you must consult with your physician if you have this condition. Anyone under the age of 18 should consult with their physician and their parents or legal guardian before beginning such a diet]. Use of Ketogenic Girl videos are subject to the Ketogenicgirl.com Terms of Use and Medical Disclaimer. All rights reserved. If you do not agree with these terms, do not listen to, or view any Ketogenic Girl podcasts or videos. -
41 min
Gut Health Gurus Podcast
Gut Health Gurus Podcast
Kriben Govender
Dr Ken Mcgrath on The Microbiome and Sports Performance
A ground breaking discussion with Dr Ken McGrath from Microba on how to optimise your microbiome, histamine, microbiome enhancement for sport performance and much more.     Bio:    Dr Ken McGrath is a specialist in molecular genomics and the clinical application of innovative technology to healthcare and partner products. With a background in molecular genomics and more than 14 years’ experience across lab management, operations management of genomics services, customer service and project management, Dr McGrath is well-placed to lead the Platform Services team. He brings his expertise in analysis and service to international partnerships applying Microba’s proprietary analysis platform to new products. Dr McGrath is also a key education provider for healthcare practitioners in the use of the company’s gut microbiome reports and the role of the gut microbiome in health and disease states and providing partners with education content to suit their needs. He has been a member of several international microbiome research projects, including monitoring antibiotic resistance through the Australian OUTBREAK initiative and US-based MetaSUB projects.     Topics discussed:   * Ken origin story * What is the Soil Microbiome ? * How microbes impact plants * Mycorrhizal Fungals * Jock Leys on Mycorrhizal Fungi https://podcast.nourishmeorganics.com.au/the-future-of-farming-soil-probiotics * Gardening * Diversity of Plant Foods in the Diet * How to increase plant food diversity * Nature and Mental Health * Probiotics and Colonisation of the Gut * Lactobacillus are Transient * Why it is important to consume Fermented Foods * The Benefits of Dead Bacteria * Why is Histamine? * Histamine Reactions * Histamine Receptors and Sensitivity * Histamine producing bacteria * How to establish that you are histamine intolerant * IBD, IBS ,Crohns Colitis detection * The future of Metagenomic Sequencing * Microbiome Testing and Sports Science * Individualised Sport Science and Nutrition * Microbiome, Lung Capacity and Endurance * The Importance of Short Chain Fatty Acids * LPS * Marathon runners and Veillonella atypica * Sports Probiotics * Gut Microbiome Doping * Microbiome and Weight Loss * Akkermansia muciniphila * Prebiotics * Working with a Microbiome Practitioner  Brought to you by:   Nourishme Organics your online shop for Gut Health Products   https://www.nourishmeorganics.com.au/   Shop online today and use code ken for 10% off   https://www.nourishmeorganics.com.au/   Connect with Dr Ken McGrath   Website: https://insight.microba.com/   Connect with Kriben Govender:    Facebook- https://www.facebook.com/guthealthgurus Instagram- https://www.instagram.com/guthealthgurus Youtube-https://www.youtube.com/c/guthealthgurus?sub_confirmation=1 Gut Health Gurus Facebook Group: https://www.facebook.com/groups/nourishmeorganics/ Deuterium Depletion Support Group : https://www.facebook.com/groups/mitowellness/   Download links               If you enjoyed this episode and would like to show your support:   1) Please subscribe on Apple Podcasts, give us 5 stars and leave a positive review     Instructions:   - Click this link  https://itunes.apple.com/au/podcast/gut-health-gurus-podcast/id1433882512?mt=2   - Click "View in Itunes" button on the left-hand side - This will open the Itunes app - Click the "Subscribe" button - Click on "Ratings and Reviews" tab - Click on "Write a Review" button   Non-Itunes users can leave a Google Review here: https://goo.gl/9aNP0V     2) Subscribe, like and leave a positive comment on Youtube   https://www.youtube.com/channel/UCq5KxLvGIY4r6SqNaAphEUw?sub_confirmation=1   3) Share your favourite episode on Facebook, Instagram, and Stories 4) Let your friends and family know about this Podcast by email, text, messenger etc   Thank you so much for your support. It means the world to us.
37 min
Nourish Balance Thrive
Nourish Balance Thrive
Christopher Kelly
Omega-3 Fatty Acids: The Best Sources, Benefits, and How To Get Enough
It would be hard to find any health practitioner - traditional, functional, or otherwise - who doesn’t acknowledge the importance of consuming omega-3 fatty acids. Supplements in the form of fish oil or krill oil are widely recommended and consumed, and come with claims of cardiovascular disease prevention, cognitive benefits, and anti-inflammatory properties. But is it really a good idea to get your omega-3s in a gel cap rather than from food? And do they really do everything the media would have you believe? On this podcast, NBT Scientific Director Megan Hall and I discuss omega-3 fatty acids: what they are, what they’re good for, and the best ways to get them. Megan outlines the different types of omega-3 and explains why some are better than others. She also explains why some health claims are overblown, and why buying fish oil supplements may not be the best health strategy. Be sure to follow along with Megan’s outline for this podcast.  Here’s the outline of this interview with Megan Hall: [00:04:30] Blood flow restriction (BFR) training; Podcast: Blood Flow Restriction Training for Improved Strength, Performance, and Healthspan with Dr Jim Stray-Gundersen MD. [00:04:51] Podcast: Wired to Run: Why Your Brain Needs Exercise, David Raichlen. [00:05:41] What are omega-3 fatty acids? [00:06:31] Picture of omega-3 fatty acids. [00:08:40] Finding omega-3s in the diet; Review: Saini, Ramesh Kumar, and Young-Soo Keum. "Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance—A review." Life sciences 203 (2018): 255-267. [00:09:16] Poor conversion from ALA to EPA/DHA: Gerster, Helga. "Can adults adequately convert a-linolenic acid (18: 3n-3) to eicosapentaenoic acid (20: 5n-3) and docosahexaenoic acid (22: 6n-3)?." International journal for vitamin and nutrition research 68.3 (1998): 159-173. [00:10:56] Why EPA and DHA are important. [00:11:38] Conditions associated with inadequate omega-3 intake. [00:12:02] Whole foods vs. supplements; other micronutrients. [00:12:42] Krill oil vs. fish oil; Studies: 1. Ulven, Stine M., et al. "Metabolic effects of krill oil are essentially similar to those of fish oil but at lower dose of EPA and DHA, in healthy volunteers." Lipids 46.1 (2011): 37-46. 2. Schuchardt, Jan Philipp, et al. "Incorporation of EPA and DHA into plasma phospholipids in response to different omega-3 fatty acid formulations-a comparative bioavailability study of fish oil vs. krill oil." Lipids in health and disease 10.1 (2011): 1-7. 3. Maki, Kevin C., et al. "Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women." Nutrition research 29.9 (2009): 609-615. 4. Mödinger, Yvonne, et al. "Plasma kinetics of choline and choline metabolites after a single dose of SuperbaBoostTM krill oil or choline bitartrate in healthy volunteers." Nutrients 11.10 (2019): 2548. [00:16:59] Megan's outline for this podcast. [00:18:21] Algae-based omega-3 supplements. [00:19:40] Omega 6:3 ratio; Paper: Simopoulos, Artemis P. "The importance of the ratio of omega-6/omega-3 essential fatty acids." Biomedicine & pharmacotherapy 56.8 (2002): 365-379. [00:25:54] Should we be supplementing with grams of fish oil? Studies: 1. De Magalhães, João Pedro, et al. "Fish oil supplements, longevity and aging." Aging (Albany NY) 8.8 (2016): 1578. 2. Strong, Randy, et al. "Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer." Aging cell 15.5 (2016): 872-884. 3. López-Domínguez, José A., et al. "The influence of dietary fat source on life span in calorie restricted mice." Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences 70.10 (2015): 1181-1188. [00:27:42] No support for omega-3 (fish oil) in the prevention of cardiovascular disease; Meta-analysis: Aung, Theingi, et al. "Associations of omega-3 fatty acid supplement use with cardiovascular disease risks: meta-analysis of 10 trials involving 77 917 individuals." JAMA cardiology 3.3 (2018): 225-233. [00:29:12] Signs you're supplementing too much fish oil. [00:30:26] Podcast: How Oxidative Stress Impacts Performance and Healthspan [00:30:43] Elevated blood glucose omega-3 supplementation; Study: Friday, Karen E., et al. "Elevated plasma glucose and lowered triglyceride levels from omega-3 fatty acid supplementation in type II diabetes." Diabetes care 12.4 (1989): 276-281. [00:31:01] Immunosuppressive effects of supplementing omega-3s: Fenton, Jenifer I., et al. "Immunomodulation by dietary long chain omega-3 fatty acids and the potential for adverse health outcomes." Prostaglandins, Leukotrienes and Essential Fatty Acids 89.6 (2013): 379-390. [00:34:17] Stages of life when omega-3s are especially important. [00:34:48] Specialized pro-resolving mediators; STEM Talk podcast episode: David LeMay Talks About Countering Inflammation with SPMS. [00:35:31] DHA to mitigate traumatic brain injury; Study: Bailes, Julian E., and Vimal Patel. "The potential for DHA to mitigate mild traumatic brain injury." Military medicine 179.suppl_11 (2014): 112-116. [00:35:45] DHA for cognitive function and aging; Study: Weiser, Michael J., Christopher M. Butt, and M. Hasan Mohajeri. "Docosahexaenoic acid and cognition throughout the lifespan." Nutrients 8.2 (2016): 99. [00:37:20] omega-3s for athletic performance; Review: Gammone, Maria Alessandra, et al. "Omega-3 polyunsaturated fatty acids: benefits and endpoints in sport." Nutrients 11.1 (2019): 46. [00:38:54] omega-3s during pregnancy; Studies: Greenberg, James A., Stacey J. Bell, and Wendy Van Ausdal. "Omega-3 fatty acid supplementation during pregnancy." Reviews in obstetrics and Gynecology 1.4 (2008): 162; 2. Braarud, Hanne Cecilie, et al. "Maternal DHA status during pregnancy has a positive impact on infant problem solving: a Norwegian prospective observation study." Nutrients 10.5 (2018): 529. [00:39:44] Excess omega-3 consumption during pregnancy could be detrimental to offspring; Study: Church, M. W., et al. "Excess omega-3 fatty acid consumption by mothers during pregnancy and lactation caused shorter life span and abnormal ABRs in old adult offspring." Neurotoxicology and teratology 32.2 (2010): 171-181. [00:40:12] Testing: The Omega Index test; Framingham Heart Study: Harris, William S., et al. "Erythrocyte long-chain omega-3 fatty acid levels are inversely associated with mortality and with incident cardiovascular disease: The Framingham Heart Study." Journal of clinical lipidology 12.3 (2018): 718-727. [00:42:34] Bottom line: More may not be better. [00:43:09] SMASH fish - sardines, mackerel, anchovies, salmon, herring (also black cod), 3-4x/week. [00:49:30] Schedule a free 15 min call with Megan.
52 min
More episodes
Search
Clear search
Close search
Google apps
Main menu