Parkinson Disease
Play • 26 min

More than 6 million people worldwide have Parkinson disease. Even though it is classically associated with tremors, the disease has many manifestations and is very treatable for most patients. Michael S. Okun, MD, from the Department of Neurology at the University of Florida, Gainesville, discusses the pathophysiology, clinical presentation, diagnosis, and treatment of Parkinson disease.

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Parkinson Disease

AMA Manual of Style

Mayo Clinic Talks
Mayo Clinic Talks
Mayo Clinic
COVID-19 Miniseries Episode 59: Mayo Clinic Q&A - Expert Updates on COVID-19 Vaccines
This episode is shared from Mayo Clinic Q&A and was recorded on January 11, 2021. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The U.S. rollout of COVID-19 vaccines is reportedly ramping up with news that nearly all available doses will soon be released to the American public. "The new COVID-19 variants are traveling quickly, and this is a warning that we need to take precautions," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. Dr. Poland says these new variants are a consequence of an RNA virus being transmitted from human to human. "Even after we get our vaccines, we still need to wear masks out in public. We still need to maintain physical distancing. And we still need to wash our hands until about 80% of people get their COVID-19 vaccines," Dr. Poland emphasizes.In this Mayo Clinic Q&A podcast, Dr. Poland goes into detail about the COVID-19 vaccines, including "sterilizing immunity," testing for antibodies after receiving the vaccine, the possibility of booster doses in the future and much more. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
31 min
Bedside Rounds
Bedside Rounds
Adam Rodman, MD, MPH, FACP
60 - Santa's Salmonella
For a special holiday treat, we’re going to explore two tales of salmonella disease detectives -- the first about Mary Mallon (“Typhoid Mary”) and the birth of the genre; and the second about a mysterious salmonella outbreak at Massachusetts General Hospital solved with the assistance of a very jolly patient. Along the way, we’ll talk about clinical epidemiology, the long-lasting influence of Berton Roueché, and the joys of being an internist! You can sign up for the Digital Education conference at cmeregistration.hms.harvard.edu/digitaleducation. Sources: * Buckle GC, Fischer Walker CL, and Black RE, Typhoid fever and paratyphoid fever: Systematic review to estimate global morbidity and mortality for 2010.J Glob Health. 2012 Jun; 2(1): 010401. * Marineli F et al, Mary Mallon (1869-1938) and the history of typhoid fever.Ann Gastroenterol. 2013; 26(2): 132–134. * Soper GA, The Curious Career of Typhoid Mary, read on May 10, 1939 before the Section of Historical and Cultural Medicine. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1911442/pdf/bullnyacadmed00595-0063.pdf * Norrington B, Cochineal: A Little Insect Goes a Long Way, UCSB Geography. * Roueche B, The Santa Claus Culture, The New Yorker, Aug 27, 1971. * Lang DJ et al, Carmine as a Source of Nosocomial Salmonellosis, NEJM. Apr 13, 1967. * You can buy Medical Detectives here: https://www.amazon.com/Medical-Detectives-Collection-Award-Winning-Investigative/dp/0452265886
38 min
The Curbsiders Internal Medicine Podcast
The Curbsiders Internal Medicine Podcast
The Curbsiders Internal Medicine Podcast
#252 Smoking Cessation Unfiltered
Get all the details on varenicline, nicotine replacement therapy, and integrating psychosocial interventions into a comprehensive smoking cessation treatment plan! Smoking cigarettes is the leading cause of preventable death worldwide. Listen as our esteemed guest Dr. Steve Baldassarri (Yale) (https://medicine.yale.edu/profile/stephen_baldassarri/) provides us expert pearls to help our patients quit smoking.  Episodes (https://thecurbsiders.com/episode-list) | Subscribe (https://anchor.fm/s/4108bcf4/podcast/rss) | Spotify (https://open.spotify.com/show/3SKlzOLxyztvA1BkJfnf67) | Swag! (https://www.teepublic.com/user/kashlakmemorial) | Top Picks (https://thecurbsiders.com/top-picks) | Mailing List (https://thecurbsiders.com/knowledgefood) | thecurbsiders@gmail.com (mailto:thecurbsiders@gmail.com) | Free CME! (http://curbsiders.vcuhealth.org) Credits Written and produced by: Carolyn Chan, MD Infographic: Edison Jyang Cover Art: Kate Grant Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Editor: Cyrus Askin, MD (written materials); Clair Morgan of nodderly.com (https://www.nodderly.com/) Guest: Steve Baldassarri MD MHS Sponsor: The American College of Physicians Join us for ACP Internal Medicine Meeting 2021: Virtual Experience for 3 days of interactive, livestreaming education and events April 29 through May 1—plus on-demand post-meeting access to CME credit for up to 3 years.   “Early Bird” members get an additional $80 registration discount on top of their member discount. Visit annualmeeting.acponline.org (https://annualmeeting.acponline.org/?utm_source=curbsiders&utm_medium=banner&utm_campaign=MD0020-6) . (Prices shown online at registration pages reflect Discounted Rates.)   Register now (https://annualmeeting.acponline.org/?utm_source=curbsiders&utm_medium=banner&utm_campaign=MD0020-6) —Early Bird savings end January 31st! Sponsor: VCU Health CE The Curbsiders are partnering with VCU Health Continuing Education (https://cme.vcuhealth.org/) to offer FREE continuing education credits for physicians and other healthcare professionals. Visit http://curbsiders.vcuhealth.org. Time Stamps* *Note: Time Stamps refer to ad free version.  03:02 Intro, disclaimer, guest bio 04:35 Guest one-liner  09:50 Tobacco Use Disorder - Chronic Disease 11:08 Case from Kashlak 11:56 Obtaining a history 13:39 Motivations for Smoking Cessation 15:29 Factors associated with challenges in smoking cessation: 21:40 Gradual Tapers vs Cold Turkey 25:18 Nicotine Replacement 32:40 28:57 Pharmacotherapy - “Controller” Medications 31:05 Pharmacotherapy - Short Acting Medications 33:20 Dosing Medications 38:35 Varenicline 39:00 Nicotine gum dosing  44:40 Duration of therapy 48:08 Bupropion  49:05 Behavioral Interventions 55:24 Vaping and electronic cigarettes  57:03 Vaping for smoking cessation 01:02:35 EVALI 01:05:49 Outro
1 hr 8 min
BrainWaves: A Neurology Podcast
BrainWaves: A Neurology Podcast
Jim Siegler, MD | Neurologist | Father | Friend of dogs
#33 Controversies in chronic traumatic encephalopathy
Almost 5 years ago, we published a show on chronic traumatic encephalopathy and its relationship to American football. But a lot has happened since 2016. New rules in the NFL. Emerging data on how the developing human brain of a child or adolescent is even more vulnerable to pathologic changes following mild head injury. And a heightened awareness of the disingenuous campaign against contact sports among one of the most outspoken whistleblowers in the medical field. This week on the program, we have remastered and updated the 2016 program. With some additional commentary on how parenthood may yield a new perspective on contact sports. Produced by James E. Siegler. Music courtesy of Chris Haugen, Kevin McLeod, and Meydan. The opening theme was composed by Jimothy Dalton. Sound effects by Mike Koenig and Daniel Simion. Unless otherwise mentioned in the podcast, no competing financial interests exist in the content of this episode. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCES * Montenigro PH, Corp DT, Stein TD, Cantu RC and Stern RA. Chronic traumatic encephalopathy: historical origins and current perspective. Annu Rev Clin Psychol. 2015;11:309-30. * Giza CC, Kutcher JS, Ashwal S, Barth J, Getchius TS, Gioia GA, Gronseth GS, Guskiewicz K, Mandel S, Manley G, McKeag DB, Thurman DJ and Zafonte R. Summary of evidence-based guideline update: evaluation and management of concussion in sports: report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology. 2013;80:2250-7. * Guskiewicz KM, Marshall SW, Bailes J, McCrea M, Cantu RC, Randolph C and Jordan BD. Association between recurrent concussion and late-life cognitive impairment in retired professional football players. Neurosurgery. 2005;57:719-26; discussion 719-26. * Stamm JM, Bourlas AP, Baugh CM, Fritts NG, Daneshvar DH, Martin BM, McClean MD, Tripodis Y and Stern RA. Age of first exposure to football and later-life cognitive impairment in former NFL players. Neurology. 2015;84:1114-20. * Ling H, Morris HR, Neal JW, Lees AJ, Hardy J, Holton JL, Revesz T and Williams DD. Mixed pathologies including chronic traumatic encephalopathy account for dementia in retired association football (soccer) players. Acta Neuropathol. 2017;133:337-352. * Alosco ML, Mez J, Tripodis Y, Kiernan PT, Abdolmohammadi B, Murphy L, Kowall NW, Stein TD, Huber BR, Goldstein LE, Cantu RC, Katz DI, Chaisson CE, Martin B, Solomon TM, McClean MD, Daneshvar DH, Nowinski CJ, Stern RA and McKee AC. Age of first exposure to tackle football and chronic traumatic encephalopathy. Annals of neurology. 2018;83:886-901. * Hobson W. "From Scientist to Salesman". Available online at https://www.washingtonpost.com/graphics/2020/sports/cte-bennet-omalu/. Accessed 31 December 2020.
19 min
Cardionerds: A Cardiology Podcast
Cardionerds: A Cardiology Podcast
CardioNerds
98. Personalized Risk Assessment for Cardiovascular Prevention with Dr. Amit Khera
CardioNerds (Carine Hamo, Amit Goyal and Daniel Ambinder) discuss personalized risk assessment for cardiovascular prevention with Dr. Amit Khera, the immediate past president for the American Society for Preventive Cardiology and Director of the Preventive Cardiology and Professor of Medicine at the University of Texas, Southwestern Medical School in Dallas, Texas. They dive into an illuminating discussion about traditional and next generation personalization of risk assessment which covers the need for personalization, traditional risk stratification, applying risk enhancing factors for decision making, biomarkers, familial hypercholesterolemia, and the use of -Omics. This episode is the 13th and final part of our in-depth prevention series produced in collaboration with the American Society for Preventive Cardiology! Stay tuned for a bonus segment at the end of the episodeas we talk to Dr. Ankur Kalra, interventionist at the Cleveland Clinic, Podcast host of Parallax by Ankur Kalra, and founder of the non-profit startup, makeadent.org for a discussion about the CHAI (Cardiovascular Health in Asian Indians) Collaborative, an initiative that aims to identify genetic markers of heightened atherosclerosis in South Asians. Episode graphic by Dr. Carine Hamo CardioNerds Cardiovascular Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll Subscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Show notes Coming soon! Cardionerds Cardiovascular Prevention Series The Cardionerds CV prevention series  includes in-depth deep dives on so many prevention topics including the ABCs of prevention, approach to obesity, hypertension, diabetes mellitus and anti-diabetes agents, personalized risk and genetic risk assessments, hyperlipidemia, women’s cardiovascular prevention, coronary calcium scoring and so much more! We are truly honored to be producing the Cardionerds CVD Prevention Series in collaboration with the American Society for Preventive Cardiology! The ASPC is an incredible resource for learning, networking, and promoting the ideals of cardiovascular prevention! This series is kicked off by a message from Dr. Amit Khera, President of the American Society for Preventive Cardiology and President of the SouthWest Affiliate of the American Heart Association. Guest Profiles Amit Khera, MD, MSc, FACC, FAHA, FASPC Dr. Amit Khera is Professor of Medicine at the University of Texas, Southwestern Medical School in Dallas, Texas where he serves as Director of the Preventive Cardiology, and holder of the Dallas Heart Ball Chair in Hypertension and Heart Disease.  He is also currently President of the American Society for Preventive Cardiology and President of the SouthWest Affiliate of the American Heart Association. His clinical and research interests include the primary and secondary prevention of coronary artery disease, focusing on risk assessment and risk factor modification in those with premature and familial disease. Dr. Khera received his undergraduate degree in American History from the University of Pennsylvania, with magna cum laude honors. He obtained his medical degree from Baylor College of Medicine where he served as class president and was inducted into the Alpha Omega Alpha honor medical society. He completed an Internal Medicine Residency at Brigham and Women’s Hospital, Harvard Medical School, followed by a Cardiology Fellowship at the University of Texas, Southwestern Medical Center. He also completed his Masters degree in Epidemiology at the Harvard School of Public Health. He has published over 150 publications in the field of preventive cardiology and has served on numerous local and national committee and leadership roles for the American Heart Association, American College of Cardiology, and American Society for Preventive Cardiology.
1 hr 9 min
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