Practitioners routinely wrestle with the issue of medication aberrant behavior (MAB)—What should I do about this? Should I discharge the patient? Will I get in trouble if I don't discharge this patient? Often there is no one right answer, and practitioners struggle with what to do in the face of a failed drug screen or some other evidence of MAB. This session will help prescribers decrease and prevent MAB in their practice as well as be more comfortable making clinical decisions when faced with MAB. The session will address such issues as universal precautions, assessing risk of MAB, clinical decision-making with regards to MAB, and deciding when to discontinue opioids. The session is designed to move practitioners from a simple "I'll discharge anyone who does anything wrong" to a more balanced and clinically sound decision-making practice.